Users who can manually edit the Reviewers are as follows:
Administrators can add/remove Reviewers
Auditors and Watchers cannot add/remove Reviewers
Eligible Reviewers can reassign the review to another user, and can add other users as a Reviewer
Eligible Reviewers can only remove those Reviewers they have added
The Requester cannot add/remove Reviewers
Users who are the only Reviewer cannot remove themselves without setting a replacement
A user who is already a Reviewer cannot be added again manually as a Reviewer